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VOLUME 7 , ISSUE 1 ( 2017 ) > List of Articles
Keywords : Antimicrobial resistance, Intestinal microbiome mobile element database, Mobile genetic elements, Split read insertion detection.
Citation Information : Sood A. Databases for Antimicrobial Resistance Genes and Mobile Genetic Elements in Gut Microbiome. J Gastrointest Infect 2017; 7 (1):41-42.
License: CC BY-SA 4.0
Published Online: 01-12-2017
Copyright Statement: Copyright © 2017 Jaypee Brothers Medical Publishers (P) Ltd.
The human gut microbiota forms a large reservoir of antimicrobial resistance (AMR) genes. Also a number of these bacteria are endowed with metabolic potentials and added advantages which are often provided by mobile genetic elements (MGE). MGEs carry out extensive horizontal gene transfer (HGT) in gut and are believed to be agents of open source evolution. Regardless of their medical importance and biological significance, MGEs from the gut microbiome have not been methodically characterized. This research news scan highlights the Intestinal microbiome mobile element database (ImmeDB) associated with the collection, classification, and annotation of MGEs from gut microbiome using a novel “deletion-based” Split Read Insertion Detection (SRID) method. The database can help us screen already identified genomes for the validation and detection of new MGEs
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