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VOLUME 8 , ISSUE 1 ( December, 2018 ) > List of Articles
Keywords : Antimicrobial resistance, Evolution-proof antibiotics, Horizontal gene transfer
Citation Information : Sood A. Evolution-proof Antibiotics. J Gastrointest Infect 2018; 8 (1):51-51.
License: CC BY-NC 4.0
Published Online: 01-12-2018
Copyright Statement: Copyright © 2018; Jaypee Brothers Medical Publishers (P) Ltd.
Evolving resistance in pathogenic bacteria has compromised the efficacy of current antibiotics. The need of the hour dictates producing antibiotics to which the bacteria cannot produce resistance. Attractive options possible are first, formulating ‘evolution-proof’ antibiotics via mutation or horizontal gene transfer which bacteria cannot resist and secondly by producing compounds to which resistance may develop, but rarely at a rate that can make it become epidemic.
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