Amebic liver abscess is the most common extraintestinal manifestation of amebiasis. It is seen most frequently in the fourth and fifth decades of life and is more common among adult men and alcoholics. The infection is primarily transmitted by food and water contamination. It presents commonly with fever and right hypochondriac pain but can present with complications like rupture into the pleural and peritoneal cavity or with abdominal vein thrombosis. The infection still responds well to nitroimidazoles, which remain the mainstay of treatment. In India, the epidemiology and presentation of amebic abscess have not changed over the years and it still is the major cause of liver abscesses.
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