Journal of Gastrointestinal Infections

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VOLUME 4 , ISSUE 1 ( 2014 ) > List of Articles

ORIGINAL ARTICLE

Trends of Hepatitis A & E Infection in a Tertiary Care Hospital of North India

Deepinder Kaur, Veenu Gupta, Rajoo Singh Chhina, Jyoti Chaudhary, Manisha Aggarwal, Kanwaldeep Lyall

Citation Information : Kaur D, Gupta V, Chhina RS, Chaudhary J, Aggarwal M, Lyall K. Trends of Hepatitis A & E Infection in a Tertiary Care Hospital of North India. J Gastrointest Infect 2014; 4 (1):44-46.

DOI: 10.5005/jp-jogi-4-1-44

License: CC BY-SA 4.0

Published Online: 00-12-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Background & Objectives: Acute viral hepatitis (AVH) is a systemic infection affecting the liver predominantly. It is a major public health problem in India and other developing nations having inadequate sanitary conditions. This study was undertaken to determine the trends of Hepatitis A & E & their coinfection in a tertiary care hospital so that appropriate management of cases as well as prevention can be planned. Material & Methods : Over a 2-year period, a total of 5894 serum samples were collected from clinically suspected cases of hepatitis. The serum samples were screened for IgM anti-HAV and IgM anti-HEV. Seasonal variation & age group wise seropositivity of hepatitis A&E was studied. Results: Out of the total 5894 samples screened, the percentage positivity of Hepatitis A was 6.7%, 6.2% and Hepatits E was 14.1%, 13.9% respectively in 2012 & 2013. Of both Hepatitis A & E positive cases, males outnumbered females. Majority of HAV positive cases were children whereas majority of hepatitis E positive cases were adults. Interpretation & Conclusion: The prevalence of HEVwas more than HAVin enterally transmitted viruses, making them a major public health problem in our area. Seasonal trends of infection were observed in addition, co-infection though infrequent, but still detected in many cases.


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  1. Gupta S, Jain P, Jain A, Prakash S, Shrivastava S, Singh KPet al. Prevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, hepatitis D virus and hepatitis E virus as causes of acute viral hepatitis in North India: A hospital based study. Indian Journal of Medical Microbiology, Vol. 31, No. 3, July- September, 2013, pp. 261-5.
  2. Acharya SK, Batra Y, Bhakal B. Sero epidemiology of hepatitis A virus infection among school children in Delhi; implications for HAV vaccination. J Gastroenterol Hepatol 2003;18:822-7.
  3. Mohanavalli B, Dhevahi E, Menon T, Malathi S, Thyagarajan SP. Prevalence of Antibodies to Hepatitis Aand Hepatitis E virus in urban school children in Chennai. Indian Pediatr 2003; 40:328-31.
  4. Nandi B, Hadimani P, Arunachalam R, Ganjoo Rk. Spectrum of acute viral hepatitis in Southern India. MJAFI 2009;65(1):7-9.
  5. Singh J, Prakash C, Gupta RS, Bora D, Jain DC, Datta KK. Epidemiology of endemic viral hepatitis in an urban area of India: a retrospective community study in Alwar. Bull World Health Organ 1997;75(5):463-8.
  6. Subrat Kumar, Radha Kanta Ratho, Yogesh Kumar Chawla, Anuradha Chakraborti. The incidence of sporadic viral hepatitis in North India: a preliminary study. Hepatobiliary Pancreat Dis Int 2007; 6: 596-9.
  7. Suri P, Chhina D, Gupta V, Singh J, Chopra P, Singh R et al. seroprevalence of Parenterally and Enterallt transmitted hepatitis viruses in a tertiary care hospital of North India- Atwo year study. J of Gastro infs 2012;2;46-51.
  8. Ippagunta SK, Naik S, Sharma B, Aggarwal R. presence of hepatitis E virus in sewage in Northern India: frequency and seasonal pattern. J Med Virol 2007;79(12):1827-31.
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