Journal of Gastrointestinal Infections

Register      Login

VOLUME 3 , ISSUE 1 ( 2013 ) > List of Articles

BRIEF COMMUNICATION

Detection of Clostridium difficile toxins A & B

Madhu Sharma, Uma Chaudhary, Aparna *, Sarita Yadav, Aakanksha *

Keywords : CDAD, C. difficile, toxin

Citation Information : Sharma M, Chaudhary U, * A, Yadav S, * A. Detection of Clostridium difficile toxins A & B. J Gastrointest Infect 2013; 3 (1):64-65.

DOI: 10.5005/jogi-3-1-64

License: CC BY-SA 4.0

Published Online: 00-07-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Clostridiumdifficile (C. difficile) is responsible for nosocomial diarrhoea and is themajor cause of pseudomembranous colitis. Incidence of C. difficile associated diarrhoea (CDAD) has increased in recent years and is associated with high mortality of 24-38%. Forty nine stool samples received were screened for the presence of C. difficile toxin A & B by ELISA, out of which 10 samples were positive for both the toxins. Therefore, CDAD needs to be diagnosed early in hospital settings so that cases can be treated early and spread can be prevented.


PDF Share
  1. Kaneria MV, Paul S. Incidence of Clostridiumdifficile associated diarrhoea in a tertiary care hospital. J Assoc Physicians India 2012;60:26-8.
  2. Vaishnavi C. Established and potential risk factors for Clostridium difficile infection. Indian J Med Microbiol 2009;27:289-300.
  3. Soman R, Sunavala A. Clostridiumdifficile infection – Is it coming at us? J Assoc Physicians India 2012;60:9-10.
  4. Ingle M, Deshmukh A, Desai D, Abraham P, Joshi A, Rodrigues C, et al. Prevalence and clinical course of Clostridium difficile infection in a tertiary care hospital: a retrospective analysis. Indian J Gastroenterol 2011;30:89-93.
  5. Chaudhary R, Joshy L, Kumar L, Dhawan B. Changing pattern of Clostridium difficile associated diarrhoea in a tertiary care hospital: a 5 year retrospective study. Indian J Med Res 2008;127:377-82.
  6. Deneve C, Janoir C, Poilane I, Fantinato C, Collignon A. New trends in Clostridium difficile virulence and pathogenesis. Int J Antimicrob Agents 2009;33:S24-8.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.