Journal of Gastrointestinal Infections

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VOLUME 3 , ISSUE 1 ( 2013 ) > List of Articles


Detection of Clostridium difficile toxins A & B

Madhu Sharma, Uma Chaudhary, Aparna *, Sarita Yadav, Aakanksha *

Keywords : CDAD, C. difficile, toxin

Citation Information : Sharma M, Chaudhary U, * A, Yadav S, * A. Detection of Clostridium difficile toxins A & B. J Gastrointest Infect 2013; 3 (1):64-65.

DOI: 10.5005/jogi-3-1-64

License: CC BY-SA 4.0

Published Online: 01-07-2013

Copyright Statement:  Copyright © 2013; Jaypee Brothers Medical Publishers (P) Ltd.


Clostridiumdifficile (C. difficile) is responsible for nosocomial diarrhoea and is themajor cause of pseudomembranous colitis. Incidence of C. difficile associated diarrhoea (CDAD) has increased in recent years and is associated with high mortality of 24-38%. Forty nine stool samples received were screened for the presence of C. difficile toxin A & B by ELISA, out of which 10 samples were positive for both the toxins. Therefore, CDAD needs to be diagnosed early in hospital settings so that cases can be treated early and spread can be prevented.

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