Journal of Gastrointestinal Infections

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VOLUME 10 , ISSUE 1 ( January-December, 2020 ) > List of Articles

REVIEW ARTICLE

Fecal Microbiota Transplantation in Intestinal Disorders: A Primer for Physicians

Arshdeep Singh, Vandana Midha, Harmeet Kaur, Ajit Sood

Keywords : Clostridioides difficile infection, Fecal microbiota transplantation, Inflammatory bowel disease, Irritable bowel syndrome, Ulcerative colitis

Citation Information : Singh A, Midha V, Kaur H, Sood A. Fecal Microbiota Transplantation in Intestinal Disorders: A Primer for Physicians. J Gastrointest Infect 2020; 10 (1):16-25.

DOI: 10.5005/jp-journals-10068-3041

License: CC BY-NC 4.0

Published Online: 29-12-2020

Copyright Statement:  Copyright © 2020; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Gut microbiota has emerged as an important player in the pathogenesis of various intestinal and extraintestinal diseases. Microbiota-targeted therapies, such as probiotics, prebiotics, antibiotics, dietary interventions, and fecal microbiota transplantation (FMT), are therefore being considered and tested as therapies for such diseases. In this review, we discuss the mechanisms and clinical applications of FMT with focus on Clostridioides difficile infection, inflammatory bowel disease, and irritable bowel syndrome. We also discuss practical issues concerning the clinical use of FMT.


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